Most spider bites will have two distinct puncture wounds. This is because they have fangs in the front that they use to grab and inject their prey with. These fangs become self defense weapons with us because naturally a spider is not going to go after a prey our size.

The wounds will usually be inflamed but one will be more severe. At times the wound will itch but not swell up or show signs of poison for a couple of days. Then it will get worse. This is actually a bacteria problem and not spider poison. The fangs have been in dead flies and other bacteria covered carcasses as the spider consumed them. Those fangs with bacteria, were then cut through your epidermis introducing the bacteria into your skin. Now you have a bacterial infection. So treat it as such.
Then there are severe wounds from the Hobo and Recluse spiders. These use a toxin that breaks down the tissue of their prey so they can eat the prey. However as a self defense weapon it goes into our cell structure and breaks down our skin and refuses to heal, making large open wounds.
This is a illustration of the stages that kind of bite can go through. This is a case that you must seek medical attention. If you take a spider bite into a doctor, do not expect them to be able to identify the type of spider. Even if you caught the spider, doctors are not trained in arachnoid identification. Better to I.D. the spider on line and then show the pictures and the information on that type of spider.